Anti-ITGA6 Antibody [Assigned #A3611]

This unconjugated mouse monoclonal antibody, distributed by Antibodies.com, targets the human integrin α6 (ITGA6) subunit, also known as CD49f. ITGA6 heterodimerizes with integrin β1 or β4 to form surface laminin receptors that mediate adhesion to basement membrane components, and altered ITGA6 expression has been reported in squamous cell carcinoma, glioblastoma, and stem-like cancer cell populations. The IgG isotype reagent is supplied as a 100 µl liquid aliquot and is validated for Western blot, immunohistochemistry, immunofluorescence, and flow cytometry applications using human samples. Researchers commonly apply it to characterize epithelial basement-membrane interactions, isolate putative stem cell populations by surface-marker profiling, and probe tumor invasion models in vitro. The assigned clone identifier is A3611, with reactivity confirmed against human ITGA6.