Anti-ITGA3 Antibody

Produced by Antibodies.com, this rabbit polyclonal antibody recognizes the human integrin alpha-3 subunit (ITGA3), a type I transmembrane glycoprotein that pairs with integrin beta-1 to assemble the α3β1 heterodimer, a principal receptor for laminin isoforms in basement membranes. The IgG isotype reagent is supplied unconjugated in a 200 µl volume and is validated for western blot detection of ITGA3 in human cell lysates and tissue homogenates. Researchers studying epithelial adhesion, kidney glomerular organization, pulmonary alveolar function, and cutaneous basement membrane biology will find this reagent relevant, as ITGA3 is strongly expressed in polarized epithelia. The antibody is also applied to investigations of tumor cell invasion, integrin-mediated cytoskeletal signaling, and pathways that link extracellular matrix contact to focal adhesion kinase activation. As a polyclonal reagent, it offers broad epitope coverage on the target protein, supporting reproducible detection across blotting conditions and lysate preparations from human research samples.