Anti-ITGA3 Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets human integrin alpha-3 (ITGA3), a type I transmembrane glycoprotein that pairs with beta-1 integrin subunits to mediate cell-matrix adhesion. Supplied as an unconjugated IgG preparation at 100 µl per vial, it is validated for Western blot detection on human samples, including cultured epithelial cells and carcinoma-derived lines commonly used in adhesion and invasion research.

ITGA3, also known as CD49c and the alpha chain of VLA-3, binds laminins, fibronectin, and certain collagens, anchoring epithelial cells to basement membranes. Investigators studying kidney glomerular development, skin basement-membrane integrity, and tumor cell migration routinely probe ITGA3 expression with this reagent. Refrigerate the vial upon arrival, protect it from light, and aliquot if repeated use is anticipated to limit freeze-thaw cycles and preserve antibody activity across many blots.

Affinity-purified and raised against the human target, the antibody is a research use only reagent for immunoblotting of whole-cell and tissue lysates expressing ITGA3, with reactivity confirmed against the human antigen.