Anti-IRS-1 (L789) Antibody

Rabbit polyclonal IgG raised against an epitope mapping to the L789 region of insulin receptor substrate 1 (IRS-1), supplied by Antibodies.com at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approx. pH 7.2. The unconjugated reagent suits western blot and immunohistochemistry workflows that probe endogenous IRS-1 in human, mouse, and rat samples, supporting studies of insulin and IGF-1 receptor signaling through the PI3K/Akt cascade. Each vial delivers 50 µl, providing material for multiple membrane strips or paraffin sections once titrated. Short term storage at 4°C is acceptable; for longer intervals, aliquot and store frozen to limit freeze-thaw cycles and protect from light. The polyclonal antibody approach offers broad epitope coverage, useful when detecting either full-length IRS-1 or its tyrosine-phosphorylated forms in lysates and fixed tissue sections.