Anti-IRS-1 Antibody

Manufactured by Antibodies.com, this affinity-purified rabbit polyclonal reagent is raised against insulin receptor substrate 1 (IRS-1) and is validated for ELISA, Western blot (WB), immunocytochemistry/immunofluorescence (ICC/IF), and immunohistochemistry (IHC) applications. The immunogen is a synthesized peptide derived from human IRS-1 around the non-phosphorylation site of S636, and the antibody specifically detects endogenous levels of IRS-1 protein across human, mouse, and rat samples. The host species is rabbit, the clonality is polyclonal, and the isotype is IgG; the reagent is supplied unconjugated in a liquid formulation containing PBS with 50% glycerol, 0.5% BSA, and 0.02% sodium azide as a preservative. Antibody concentration is 1 mg/mL, and the 50 µL size is ideal for routine bench use. For handling and storage, the product is shipped at 4 °C and, upon receipt, should be aliquoted and stored at −20 °C, with care taken to avoid repeated freeze/thaw cycles to preserve performance. The antibody is purified from rabbit antiserum by affinity chromatography using the epitope-specific immunogen, supporting low background and strong target specificity in WB, IHC, IF, and ELISA workflows. Intended for research use only, it is not validated for diagnostic or therapeutic applications and is supplied by Antibodies.com as a primary antibody targeting the IRS-1 signaling intermediate.