Anti-IRS-1 (Ab-639) Antibody

This polyclonal antibody from Antibodies.com targets an epitope of IRS-1 (Insulin Receptor Substrate 1) corresponding to the region around residue 639 and is supplied as 100 µl of unconjugated rabbit antiserum for Western blot and immunofluorescence applications.

The reagent detects endogenous IRS-1 in human, mouse, and rat samples and supports research on insulin and IGF-1 receptor signaling, metabolic regulation, and downstream phosphorylation events triggered by growth factors, cytokines, and cellular stress. Aliquot upon receipt and store at -20 °C in single-use fractions to preserve activity; avoid repeated freeze-thaw cycles.

The unconjugated format gives research labs the flexibility to pair the antibody with their own secondary conjugates and detection chemistries for fluorescence imaging, immunohistochemistry, or chemiluminescent readouts in cell biology, endocrinology, and metabolic disease research.