Anti-IRF6 Antibody

IRF6 (Interferon Regulatory Factor 6) is a transcription factor critical for orofacial morphogenesis and epidermal keratinocyte differentiation. This polyclonal reagent from Antibodies.com is raised in rabbit hosts and targets the human and mouse IRF6 protein, which genetic studies have linked to Van der Woude syndrome, the most common syndromic form of cleft lip and palate. Recommended applications include western blot analysis of cell lysates and immunohistochemistry on fixed tissue sections, where the unconjugated format allows direct integration with secondary antibody detection chemistries of the researcher's choice. Each vial is supplied as 100 µl of liquid formulation suitable for use across multiple experiments, with reactivity validated for both human and mouse samples. Researchers investigating craniofacial development, Wnt signaling, or epithelial barrier biology may find this reagent useful for characterizing IRF6 expression patterns in developmental and disease contexts.