Anti-IRF5 Antibody

Raised in rabbit against the IRF5 transcription factor, this unconjugated polyclonal antibody from Antibodies.com is supplied as 100 µl of ready-to-use reagent for Western blot, immunohistochemistry, and immunofluorescence workflows. IRF5 (interferon regulatory factor 5) is a key mediator of innate immune signaling, driving type I interferon responses downstream of Toll-like receptor activation and governing macrophage polarization toward a pro-inflammatory M1 phenotype. The antibody cross-reacts with mouse and rat orthologues in addition to its primary reactivity with human IRF5, supporting translational studies in cell culture and tissue models of autoimmune and inflammatory disease. Supplied in a vial as a polyclonal rabbit IgG fraction, it integrates into standard immunodetection protocols without the need for secondary labeling. Store refrigerated and protect from repeated freeze-thaw cycles to preserve titer for use in signaling pathway research.