Anti-IRF4 Antibody

This rabbit polyclonal antibody from Antibodies.com targets IRF4 (Interferon Regulatory Factor 4), a transcription factor expressed primarily in lymphocytes and other immune cell lineages. The reagent is supplied as 100 µL of unconjugated antisera raised in rabbit, validated for Western blot and immunofluorescence workflows across human, mouse, and rat samples.

IRF4 acts as a key regulator of B-cell maturation, germinal center formation, plasma cell differentiation, and T-helper subset specification. Researchers studying adaptive immunity, lymphoma biology, and multiple myeloma pathogenesis rely on consistent detection of IRF4 to characterize tumor subtypes, map transcriptional programs, and investigate immune cell signaling cascades. Polyclonal recognition offers broad epitope coverage, which can be especially useful when probing truncated isoforms, post-translationally modified species, or variant splice products that monoclonal reagents may miss.

Suggested applications include Western blot validation of IRF4 expression in lymphoid lysates and immunofluorescence localization studies in fixed tissue sections or cultured immune cells. The unconjugated format allows flexible pairing with user-selected secondary reagents and detection chemistries, including HRP, fluorophore, or biotin conjugates. Aliquot upon receipt and store refrigerated to preserve antibody activity across multiple experiments.