Anti-IRF2 Antibody

This polyclonal reagent from Antibodies.com targets Interferon Regulatory Factor 2 (IRF2), a transcription factor that binds the interferon-stimulated response element (ISRE) and modulates type I interferon signaling, hematopoietic lineage decisions, and tumor suppressor programs. Produced in rabbit and supplied as an unconjugated IgG in a 200 µl volume, it is validated for western blot detection of endogenous IRF2 in human and mouse samples.

IRF2 exerts context-dependent control over NK cell maturation, Th1 polarization, and PD-L1 transcription, making antibodies against it useful in immunology, virology, and oncology research workflows. The unconjugated format permits flexible pairing with HRP, fluorescent, or biotinylated secondaries for chemiluminescent western blot, immunofluorescence, or pull-down assays. For handling, refrigerate on arrival, aliquot to limit freeze-thaw cycles, and protect from light when working with downstream fluorophore conjugates.

Researchers studying JAK/STAT signaling, antiviral defenses, or immune checkpoint regulation routinely use anti-IRF2 antibodies to map upstream drivers of innate immunity and transcriptional reprogramming in primary cells and tumor models. The unconjugated IgG format supports flexible pairing with diverse secondary reagents and detection platforms in varied experimental contexts.