Anti-IRF2 Antibody

This polyclonal reagent from Antibodies.com targets Interferon Regulatory Factor 2 (IRF2), a nuclear transcription factor that competitively occupies interferon-stimulated response elements (ISRE) and modulates type I interferon-driven gene expression. IRF2 acts as both an activator and a repressor, shaping downstream signaling cascades tied to antiviral defense, hematopoietic lineage commitment, NK and T lymphocyte maturation, and tumor-suppressor pathways.

Raised in rabbit and purified as an IgG preparation, the unconjugated antibody is supplied in a 100 µl volume and is validated for western blot detection of endogenous IRF2 in human and mouse samples. Investigators studying transcription factor crosstalk, innate immunity, chromatin occupancy, or oncogenic transformation can apply this reagent to lysates from cell culture and primary tissue, supporting work on interferon pathway regulation, immune cell development, and disease-associated changes in IRF2 expression.