Anti-IRF-5 Antibody

Raised in rabbits against a peptide region of interferon regulatory factor 5 (IRF-5), this unconjugated polyclonal primary antibody from Antibodies.com detects the endogenous transcription factor in human, mouse, and rat samples. Supplied as 100 µl of a 1 mg/ml stock in a vial of PBS containing 0.1% sodium azide and 50% glycerol, the reagent is validated for western blot, immunohistochemistry, and immunofluorescence workflows. IRF-5 drives type I interferon and inflammatory cytokine signaling in myeloid cells, and the antibody is commonly used to profile macrophage and B-cell activation states, dissect TLR and RIG-I signaling pathways, and characterize disease models involving lupus, atherosclerosis, and viral infection. The glycerol-containing formulation supports aliquoting and storage at -20 °C with minimal freeze-thaw loss, and the unconjugated format allows flexible pairing with HRP, fluorophore, or biotin secondary reagents.