Anti-IRAK1BP1 Antibody

Rabbit polyclonal reagent from Antibodies.com raised against IRAK1BP1 (interleukin-1 receptor-associated kinase 1-binding protein 1), an intracellular signaling adapter linked to IRAK1 phosphorylation, toll-like receptor signaling cascades, and NF-κB-driven transcription. Affinity-purified antiserum is supplied as 100 µl of unconjugated antibody validated for Western blot and immunohistochemistry on human and mouse specimens. The reagent supports immunoblotting of whole-cell and tissue lysates, chromogenic IHC on paraffin-embedded sections, and immunoprecipitation of endogenous IRAK1BP1 complexes from primary immune cells. Researchers use it to map IRAK1BP1 expression across hematopoietic lineages, tumor microenvironments, and inflamed epithelial tissues, where SIMPL-domain activity intersects with cytokine signaling, viral response pathways, and pattern-recognition receptor biology.