Anti-IQGAP3 Antibody

The Antibodies.com Anti-IQGAP3 polyclonal antibody is raised in rabbit and recognizes IQGAP3, a cytoskeletal scaffolding protein of the IQGAP family that interacts with small GTPases and modulates actin organization. This unconjugated IgG reagent is validated for western blot detection of endogenous IQGAP3 in human cell and tissue lysates and is supplied as a 50 µl volume in a vial format used in immunoblotting workflows.

IQGAP3 has been characterized in studies of gastric, colorectal, and hepatocellular carcinomas, where its contribution to cell migration, proliferation, and cytoskeletal remodeling has been documented. The polyclonal IgG format offers recognition of multiple epitopes on the target protein, supporting reproducible detection across research applications including cancer signaling, cytoskeletal dynamics, and cell motility studies. Researchers evaluating IQGAP3 expression in tumor models can apply this antibody to standard western blot protocols using lysates prepared from cultured human cells.

For long-term use, aliquot the antibody upon arrival and store frozen at -20°C; protect from light and minimize freeze-thaw cycles to preserve binding activity through repeated experiments.