Anti-IQGAP3 Antibody

The Antibodies.com polyclonal antibody specifically targets IQGAP3, a scaffold protein of the IQGAP family that organizes cytoskeletal dynamics, cytokinesis, and Rho-family GTPase signaling. Raised in rabbit and purified as an IgG preparation, this unconjugated reagent is supplied at 200 µl volume and is validated for western blot detection of the human protein. Researchers studying cell migration, epithelial-mesenchymal transition, and tumor cell proliferation have used IQGAP3 as a marker because it is frequently upregulated in gastric, hepatocellular, and colorectal carcinoma tissues, where its abundance correlates with advanced disease stage. The polyclonal reagent binds multiple epitopes on the IQGAP3 molecule, which can improve signal recovery in western blot when target expression is low. It is intended for research use only in laboratory applications that investigate cytoskeletal remodeling, GTPase scaffold biology, and oncology pathways linked to IQGAP3 overexpression. Each vial contains 200 µl of antibody delivered in a working volume suitable for multiple blotting experiments.