Anti-IQGAP2 Antibody

IQGAP2 is a large multidomain scaffolding protein of the IQGAP family, best known for coordinating cytoskeletal remodeling, cell-cell adhesion, and receptor signaling at the plasma membrane. Antibodies.com offers this rabbit polyclonal antibody reagent as an unconjugated format supplied at 100 µl, affinity-purified for researchers working on human samples.

The reagent is validated for Western blot (WB) and immunohistochemistry (IHC). It is useful for probing IQGAP2 expression patterns in liver, gastrointestinal, and epithelial model systems, where IQGAP2 acts as a candidate tumor suppressor in hepatocellular and gastric carcinomas and contributes to bile duct morphogenesis and platelet function in knockout studies. The polyclonal mixture targets multiple epitopes along the protein, increasing the chance of detecting full-length and partially degraded IQGAP2 across varied sample preparations.

Researchers studying hepatocyte polarity, gastric mucosal biology, or receptor tyrosine kinase signaling will appreciate this reagent. It is provided as a research use only reagent in a 100 µl vial, suitable for immunoblotting and chromogenic IHC workflows on fixed human tissue sections.