Anti-IPO5 Antibody

This polyclonal reagent from Antibodies.com targets Importin 5 (IPO5), a karyopherin-β family member that mediates nucleocytoplasmic transport of ribosomal proteins and other large cargo through the nuclear pore complex. Raised in rabbit and supplied unconjugated in a 100 µl volume, the antibody is validated for Western blot, immunohistochemistry, and immunofluorescence workflows.

The antibody recognizes the IPO5 ortholog in human, mouse, and rat samples, supporting comparative studies across common model systems. On Western blot it produces a band consistent with the predicted ~110 kDa molecular mass of full-length Importin 5, and immunofluorescence staining highlights nuclear envelope-associated signal in cultured cells. Researchers working on transport receptor biology, ribosome biogenesis, mitotic regulation, or nuclear import pathways use this reagent to assess expression, subcellular localization, and perturbation responses in cell culture and tissue sections.

Recommended handling: aliquot upon first thaw to limit freeze-thaw cycles, store refrigerated for short-term use, and protect from light when working with fluorescent secondary detection. For research use only.