Anti-IPO11 Antibody

Raised in rabbit against the human importin-11 (IPO11) nuclear transport receptor, this unconjugated IgG polyclonal reagent from Antibodies.com is supplied as a 200 µl vial of liquid suitable for western blot, immunohistochemistry, and flow cytometry workflows.

IPO11 is a member of the importin-β family of nuclear transport receptors that mediates Ran-dependent nuclear import of select cytoplasmic cargo proteins. Published studies link the receptor to trafficking of ubiquitin-conjugating enzymes and to broader regulation of nuclear protein import. The antibody is validated for human samples and supports detection of endogenous IPO11 expression in cell lysates, fixed tissue sections, and permeabilized cells.

Because the reagent is unconjugated, researchers can pair it with a secondary reporter of choice (HRP, fluorophore, or biotin) for in vitro and ex vivo assay design. Storage at -20 °C preserves activity across multiple freeze-thaw cycles; aliquoting upon first thaw is recommended to limit handling losses.