Anti-Interferon alpha-2 Antibody

An unconjugated rabbit polyclonal reagent from Antibodies.com binds the human Interferon alpha-2 (IFNA2) protein and is validated for western blot, immunohistochemistry, and immunofluorescence detection. IFNA2 is a type I interferon cytokine secreted by virus-infected leukocytes that drives antiviral signaling through JAK-STAT pathways and the induction of interferon-stimulated genes, making the target a focus of innate immunity, viral pathogenesis, and autoimmune-disease research.

Affinity-purified against the IFNA2 immunogen, the antibody recognizes multiple epitopes across the molecule, which is useful when tracking protein expression in tissue sections and confirming transcript-to-protein translation in cell-based assays. Each vial ships as a 100 µl liquid aliquot and should be stored frozen in working aliquots at -20°C to limit repeated freeze-thaw cycles; thaw only the volume needed for the experiment. The unconjugated format leaves the choice of label open for downstream coupling to HRP, fluorophore, or biotin chemistries as required by the experimental design.

Common use cases include profiling interferon-stimulated gene expression in patient-derived primary cells, mapping IFNA2-producing populations in inflamed or infected tissue by immunohistochemistry, and confirming recombinant IFNA2 production in transfected mammalian expression systems. Researchers should titrate the antibody empirically against their specific sample type and fixation protocol, as performance differs between paraffin-embedded sections, fresh-frozen tissue, and cultured cell monolayers. Intended for research use only, the reagent supports laboratory investigation of cytokine biology, antiviral immunity, and interferon pathway dysregulation in human disease.