Anti-Integrin αL Antibody

Raised in rabbit against human Integrin αL (also known as CD11a, the alpha chain of the LFA-1 integrin), this polyclonal reagent from Antibodies.com is supplied as 100 µl of unconjugated antiserum for western blot and ELISA workflows.

Integrin αL pairs with the β2 subunit (CD18) to assemble LFA-1 (CD11a/CD18), a leukocyte-restricted adhesion receptor that engages ICAM-1, ICAM-2, and ICAM-3 during immune cell migration, immunological synapse formation, and transendothelial trafficking. Researchers studying T-cell activation, neutrophil extravasation, transplant rejection, or Leukocyte Adhesion Deficiency (LAD) use this antibody to probe the CD11a subunit in human cell and tissue lysates.

The unconjugated format allows flexible pairing with HRP, fluorescent, or biotin secondary reagents depending on the assay design. Host species is rabbit, clonality is polyclonal, and reactivity is restricted to human samples. Store refrigerated and avoid repeated freeze-thaw cycles to preserve antibody activity across multiple experiments.