Anti-Integrin β1 Antibody

The recombinant monoclonal antibody from Antibodies.com targets Integrin β1, a transmembrane glycoprotein that mediates cell-extracellular matrix adhesion through heterodimeric pairing with various α subunits. Raised in rabbit and supplied as an unconjugated IgG preparation, this reagent is validated for western blot and immunohistochemistry workflows across multiple model organisms, including human, mouse, rat, and zebrafish tissue samples.

The antibody is formulated in TBS buffer (pH 7.4) supplemented with 1% BSA and 40% glycerol as a cryoprotectant, with 0.05% sodium azide added as a preservative. Each vial delivers 50 µl of ready-to-use reagent suitable for immunolabeling studies of focal adhesion complexes, epithelial-mesenchymal transition markers, and integrin-dependent signaling pathways implicated in cancer invasion, wound repair, and developmental biology research.

Integrin β1 (also designated CD29) participates in bidirectional signaling between the cytoskeleton and the extracellular environment, making it a frequent target in studies of cell migration, stem cell niche interactions, and fibrotic disease mechanisms. The recombinant production method ensures batch-to-batch consistency and avoids hybridoma-derived variability, supporting reproducible detection in phosphorylation studies, co-immunoprecipitation experiments, and tissue section analysis.