Anti-InsP 3-kinase C Antibody

Rabbit polyclonal antibody from Antibodies.com targeting InsP 3-kinase C (ITPKC), the calcium-signaling enzyme that phosphorylates inositol 1,4,5-trisphosphate to inositol 1,3,4,5-tetrakisphosphate. Raised in rabbit and supplied as an unconjugated antiserum in a 100 µl volume, this reagent is validated for Western blot, immunohistochemistry, and ELISA workflows on human samples. ITPKC modulates InsP3-driven calcium release downstream of phospholipase C activity and is studied in the context of immune cell signaling, T-cell activation, and inflammatory disease research, including Kawasaki disease susceptibility variants mapped to chromosome 19q13.4. The unconjugated format allows flexible pairing with secondary reporters of the researcher's choice, supporting detection of endogenous ITPKC across lysates, fixed tissue sections, and plate-based immunoassays.