Anti-INPP5J Antibody

This polyclonal reagent from Antibodies.com targets inositol polyphosphate 5-phosphatase J (INPP5J), a phosphatase that hydrolyzes the 5-phosphate of phosphatidylinositol 4,5-bisphosphate and related phosphoinositide substrates, modulating phosphoinositide-dependent signaling in cells. The antibody is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as a 100 µL aliquot.

Validated for Western Blot analysis of cell and tissue lysates and for Immunohistochemistry on fixed sections, the antibody cross-reacts with the human, mouse, and rat orthologs of INPP5J, supporting comparative work across model systems. The unconjugated IgG is paired with the user's own choice of HRP-, biotin-, or fluorophore-conjugated secondary reagents.

For storage, keep the stock frozen at -20 °C; the 50% glycerol acts as a cryoprotectant during freeze-thaw cycles, while the 0.1% sodium azide prevents microbial contamination of working dilutions. The polyclonal composition raises antibodies against multiple epitopes on the INPP5J protein, which is helpful when antigen accessibility varies across preparations and species.