Anti-IMPDH2 Antibody

IMPDH2 (Inosine Monophosphate Dehydrogenase 2) is the rate-limiting enzyme in de novo guanine nucleotide biosynthesis, making it a focal point in studies of lymphocyte proliferation, immunosuppressant drug response (notably mycophenolic acid inhibition), and oncogenic signaling pathways. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against human IMPDH2 and validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows across human, mouse, and rat samples.

The polyclonal format broadens epitope coverage for consistent detection in cell lysates and tissue sections, while the unconjugated presentation enables flexible pairing with custom secondary labels, including HRP, fluorophore, or biotin conjugates. Supplied as a 100 µL vial, the antibody is well suited for signal-pathway characterization, target validation studies, and investigations of IMPDH2 expression in cancer models, including leukemia and lymphoma research.

Researchers exploring guanine metabolism, mTOR-related signaling, or transplant immunology will find this reagent a practical addition to their antibody panel, with the rabbit host permitting broad compatibility with standard secondary antibody tools.