Anti-IMPA1 Antibody

The IMPA1 enzyme (Inositol Monophosphatase 1) plays a central role in the phosphatidylinositol signaling pathway by hydrolyzing inositol monophosphate to free inositol, a step required for replenishing the phosphoinositide pool that supports neurotransmitter signaling. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against IMPA1 and validated for Western blot and immunohistochemistry workflows in human, mouse, and rat samples. The antibody is supplied at 1 mg/ml in a PBS buffer containing 0.1% sodium azide and 50% glycerol as a cryoprotectant, shipped as a 100 µl liquid aliquot ready for dilution into standard blotting or staining protocols. Researchers studying lithium-sensitive phosphoinositide signaling, bipolar disorder mechanisms, or neural inositol metabolism commonly use IMPA1 immunoreagents to map protein expression across brain and peripheral tissues. Polyclonal reactivity supports recognition of multiple epitopes on IMPA1, which can improve signal in immunohistochemistry where epitope accessibility varies with fixation and tissue processing. The unconjugated format gives laboratories flexibility to conjugate the antibody to HRP, biotin, or a fluorophore of their choice depending on the downstream detection chemistry.