Anti-IL7R Antibody

Raised in rabbit against the human Interleukin-7 receptor alpha chain (commonly referred to as CD127), this unconjugated polyclonal reagent from Antibodies.com supports research into T-lymphocyte development, survival signaling through the JAK1/JAK3-STAT5 axis, and the contribution of IL7R variants to immunodeficiency syndromes such as severe combined immunodeficiency.

Validated for western blot, immunohistochemistry, and immunofluorescence on human samples, the antibody is supplied as a 100 µl vial and is provided unconjugated, allowing researchers to couple it to their preferred fluorophore or enzyme for custom detection workflows. Investigators working on T-cell acute lymphoblastic leukemia, where aberrant IL7R signaling drives leukemogenesis in a defined subset of cases, and on the regulation of CD127 surface expression across naive, memory, and effector T-cell compartments, will find this reagent a flexible primary antibody for both protein-level and tissue-localization studies.

Storage at -20 °C is recommended, and small aliquots help preserve activity across multiple freeze-thaw cycles. The polyclonal format increases the likelihood of robust signal across distinct epitopes of the IL-7 receptor extracellular domain, supporting consistent detection in varied sample preparations.