Anti-IL6 Antibody [5G8]

The 5G8 monoclonal from Antibodies.com is a mouse-derived primary antibody raised against human interleukin-6, a pleiotropic cytokine central to acute-phase signaling, B-cell maturation, and the inflammatory pathways implicated in autoimmune disease, oncology, and infectious-immune research. Produced as an unconjugated IgG1 and supplied lyophilised in a 100 µg vial, the reagent reconstitutes cleanly for downstream workflows or for pairing with user-selected detection reagents.

Validated applications span ELISA, Western blot, and flow cytometry, supporting quantitative cytokine measurement, signaling-pathway studies, and immunophenotyping of IL-6-producing cell populations. Reactivity is established against human IL-6, making the clone useful for translational programs where interleukin-6 serves as a biomarker or mechanistic readout.

As an unconjugated primary reagent, the 5G8 clone offers flexibility for custom fluorophore or enzyme conjugation, or for pairing with biotinylated secondary antibodies. Lyophilised format extends shelf stability prior to reconstitution, and aliquoting into single-use vials after resuspension helps preserve binding activity across repeat freeze-thaw cycles.