Anti-IL6 Antibody [1E3]

This Mouse monoclonal [1E3] antibody targets IL6 and is offered by Antibodies.com within their Primary Antibodies range. The reagent is of the IgG1 isotype, unconjugated, and presented in lyophilised form. It reacts with human samples and is validated for ELISA, Western blot (WB), and flow cytometry (FC), with the manufacturer providing two scientific validation images.

IL-6, also known as B-cell stimulatory factor-2 (BSF-2), is a cytokine that drives B-cell differentiation into immunoglobulin-secreting cells. It is principally produced by T-cells, macrophages, and endothelial cells in response to pathogenic molecular stimuli associated with infection, trauma, and the growth phase of certain cancers. IL-6 expression is up-regulated when Toll-like receptors engage antigen pattern ligands. During the acute inflammatory phase, IL-6 elevates body temperature by triggering Prostaglandin E2 synthesis in the hypothalamus.