Anti-IL6 Antibody [1B6]

This mouse monoclonal IgG1 antibody targets human Interleukin-6 (IL-6), a pleiotropic cytokine central to acute-phase responses, B-cell maturation, and chronic inflammatory signaling that acts through the JAK/STAT3 pathway. The unconjugated 1B6 clone from Antibodies.com supports three orthogonal workflows: ELISA for quantitative serum or supernatant measurements, Western blot for detecting the ~21 kDa IL-6 band in cell lysates, and flow cytometry for surface or intracellular staining of cytokine-producing populations.

The reagent is supplied as 100 µg of lyophilised powder in a single vial, reconstituted with sterile buffer prior to use. Researchers working on autoimmune disease models, cancer-associated inflammation, rheumatoid arthritis, or cytokine release studies use this antibody to track IL-6 expression in stimulated peripheral blood mononuclear cells, synovial fluid samples, and tumor microenvironment lysates. The lyophilised format supports ambient shipping and a long shelf life; reconstituted aliquots should be stored frozen to limit freeze-thaw cycles and preserve binding activity for downstream in vitro stimulation experiments.