Anti-IL5RA Antibody

Raised in rabbit and supplied by Antibodies.com as an unconjugated 100 µl aliquot, this polyclonal reagent targets the alpha subunit of the interleukin-5 receptor (IL5RA, also designated CD125), a type I cytokine receptor that pairs with the common beta chain CSF2RB to transduce IL-5 signaling in eosinophils and basophils. The antibody is validated for Western blot and immunohistochemistry on human and mouse specimens, making it useful for studies of eosinophil differentiation, receptor expression in allergic airway inflammation, asthma pathogenesis, hypereosinophilic syndromes, and other inflammatory disease models. Researchers apply it to confirm IL5RA abundance in lysates from primary granulocytes or eosinophilic cell models, to map receptor distribution in tissue sections, and to track modulation of IL5RA expression under cytokine challenge.