Anti-IL5 Antibody

From Antibodies.com, this rabbit polyclonal IgG antibody recognizes interleukin-5 (IL-5), the Th2-associated cytokine that drives eosinophil maturation, activation, and survival. Supplied as 50 µL of unconjugated antiserum, the reagent binds the native cytokine in human, mouse, and rat samples and has been validated for Western blot and immunohistochemistry, supporting studies of airway inflammation, allergic responses, and eosinophil-driven pathology. Because the polyclonal format presents multiple epitopes on the homodimeric cytokine, the antibody tolerates partial denaturation during SDS-PAGE sample preparation and remains useful for immunoblot detection across tissue lysates. In immunohistochemistry, the unconjugated IgG permits chromogenic or fluorescent reporter pairing in formalin-fixed paraffin-embedded sections, letting researchers localize IL-5-producing cells within lung, gastrointestinal, or other inflamed tissue biopsies. Investigators comparing Th2-skewed immune responses between species, profiling cytokine expression in asthma or helminth infection models, and validating eosinophil-related therapeutic targets routinely select unconjugated anti-IL-5 reagents of this type for their flexibility in secondary antibody selection and downstream detection chemistry.