Anti-IL3RA Antibody

Housed in a 100 µl vial, this unconjugated rabbit polyclonal reagent from Antibodies.com targets the IL3RA protein (also known as CD123), the alpha subunit of the interleukin-3 receptor. Validated for western blot and immunohistochemistry workflows, the antibody recognizes both human and mouse IL3RA, supporting translational studies that span rodent disease systems and patient-derived tissue. Polyclonal preparations typically engage multiple epitopes across the target, which can help when the antigen is partially degraded or when working with FFPE sections where epitopes may be masked by fixation. IL3RA / CD123 is widely used as a surface marker for plasmacytoid dendritic cells and is overexpressed in several hematologic malignancies, including acute myeloid leukemia and blastic plasmacytoid dendritic cell neoplasm, so this reagent fits hematopathology, immunology, and oncology research programs. Provided unconjugated to give users flexibility over detection chemistry, the antibody pairs with HRP, biotin, or fluorophore-labeled secondary reagents of the researcher's choice. For short-term use, aliquot upon arrival and store refrigerated to limit freeze-thaw cycles, which can erode polyclonal antibody activity over time.