Anti-IL36G Antibody

This polyclonal reagent from Antibodies.com is a rabbit-derived IgG antibody raised against interleukin-36 gamma (IL36G), a pro-inflammatory member of the IL-1 cytokine family implicated in epithelial barrier defense, neutrophil recruitment, and psoriatic skin inflammation. Produced as an unconjugated primary antibody, it is supplied at 50 µl per vial and validated for Western blot detection of mouse IL36G in cell lysate and tissue homogenate samples.

The antibody recognizes endogenous IL36G and supports research into cytokine signaling, inflammatory skin disease models, and host-pathogen immune responses. As a polyclonal reagent, it targets multiple epitopes on the IL36G protein, which can strengthen signal detection in Western blot workflows. The IgG isotype allows pairing with standard anti-rabbit secondary reagents and common immunoblotting detection chemistries.

Recommended protocols involve loading reduced and denatured protein samples on SDS-PAGE gels, transferring to nitrocellulose or PVDF membranes, blocking, and probing with the primary antibody followed by an HRP-conjugated anti-rabbit IgG. Store refrigerated and aliquot to limit repeated freeze-thaw cycles, which helps preserve binding activity over time.