Anti-IL31RA Antibody

This polyclonal antibody from Antibodies.com targets the human and mouse Interleukin-31 receptor subunit alpha (IL31RA), a type I cytokine receptor that mediates IL-31 signaling and is implicated in pruritus, atopic dermatitis, and epithelial barrier responses. The reagent is raised in rabbit and supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, supporting straightforward storage and handling for routine experimental workflows. Validated applications include Western blot for detection of endogenous receptor expression across cell and tissue lysates, and immunohistochemistry for visualizing IL31RA distribution in skin, lung, and neural sections. The unconjugated format gives researchers flexibility to pair the antibody with their own preferred secondary detection reagents and custom labeling strategies. A 100 ul aliquot provides sufficient volume for multiple experimental runs across different sample sets. For storage, the 50% glycerol formulation helps protect activity during standard freeze-thaw handling at laboratory freezer temperatures. The cross-reactivity profile supports detection in both human and mouse samples, enabling translational work in relevant disease models. Investigators studying cytokine-driven inflammation, dermatological disorders, or neuroimmune signaling can use this reagent to probe receptor expression patterns at the protein level.