Anti-IL27 Antibody

Raised in rabbit and supplied by Antibodies.com as an unconjugated polyclonal antiserum, this primary antibody recognizes Interleukin-27 (IL27), a heterodimeric IL-12-family cytokine assembled from EBI3 and p28 subunits. It is validated for Western blot and immunohistochemistry on human samples, with cross-reactivity toward mouse and rat orthologues that supports comparative and translational studies across species. Each vial contains 100 µl, sufficient for routine immunoblotting loading volumes and IHC staining of formalin-fixed paraffin-embedded tissue sections. IL27 detection is used to investigate Th1 and regulatory T cell differentiation, cytotoxic lymphocyte activity, and the cytokine's expanding role in autoimmune disease, chronic inflammation, and tumor immunology. The unconjugated format allows flexible pairing with HRP, biotin, or fluorophore-conjugated secondary reagents depending on the detection platform. Working aliquots are recommended to limit repeated freeze-thaw cycles, and the reagent should be refrigerated upon arrival. For research use only.