Anti-IL20 Antibody

A polyclonal reagent from Antibodies.com, this unconjugated primary antibody is raised in rabbits against human interleukin-20 (IL-20), a pro-inflammatory cytokine of the IL-10 family that drives keratinocyte hyperproliferation in psoriatic skin and contributes to synovial inflammation in rheumatoid arthritis. The antibody ships as a 100 µL volume in a single vial and is validated by the manufacturer for western blot (WB) and immunofluorescence (IF) workflows, supporting detection of endogenous IL-20 in human cell lysates, cultured keratinocytes, and fixed tissue sections. Its unconjugated format gives laboratories the flexibility to pair the reagent with HRP-, biotin-, or fluorophore-tagged secondary antibodies matched to their own detection platforms. For best long-term stability, the vial should be stored at -20 °C in working aliquots and protected from repeated freeze-thaw cycles, since polyclonal preparations lose activity with excessive thawing. Reactivity is reported for human IL-20 only; cross-reactivity with mouse or rat orthologs is not listed in the supplier's datasheet, so animal-model studies should be paired with appropriate negative and positive controls. These characteristics position the reagent for inflammatory disease research programs focused on IL-20 signalling through the IL-20R1/IL-20R2 receptor axis and downstream STAT3 activation in psoriatic, osteoarthritic, and synovial tissue models.