Anti-IL20 Antibody

This polyclonal antibody from Antibodies.com targets Interleukin-20, a cytokine in the IL-10 family that signals through IL-20R1/IL-20R2 and IL-22R1/IL-20R2 receptor complexes to drive STAT3 activation in responsive cells. Raised in rabbit and purified as a standard IgG preparation, it is supplied as 50 µl of unconjugated reagent per vial, leaving conjugation chemistry open for secondary labelling or direct detection. Researchers use it for Western blot, immunohistochemistry, and immunofluorescence, with reactivity demonstrated against human and mouse IL-20. The polyclonal format broadens epitope coverage on the target, which is helpful when endogenous IL-20 levels are low or when working with primary keratinocytes, formalin-fixed tissue sections, and mouse models of cutaneous inflammation. Practical uses include mapping IL-20 expression in psoriatic lesional skin and wound-edge epithelium, characterising STAT3 phosphorylation downstream of IL-20 receptor engagement, and screening transfected cell lines or recombinant expression constructs for protein-level expression. The unconjugated IgG format couples cleanly with anti-rabbit HRP, alkaline phosphatase, or Alexa Fluor secondaries used in standard chromogenic and fluorescence workflows, and it is compatible with reducing SDS-PAGE conditions used in routine Western blot analysis.