Anti-IL1RN Antibody

Raised in rabbit and affinity-purified against a recombinant human IL1RN immunogen, this unconjugated polyclonal reagent from Antibodies.com is supplied at a working concentration of 1.0 mg/mL in a 50 µL format, intended for the sensitive detection of endogenous IL-1 Receptor Antagonist (IL1RN / IL-1RA) in standard western blotting and immunocytochemistry workflows. Validated applications on the manufacturer's datasheet are Western Blot (WB) and Immunocytochemistry / Immunofluorescence (ICC/IF), and the antibody cross-reacts with Human, Mouse and Rat samples, making it a versatile reagent for comparative studies of inflammatory signalling across species. The host species is Rabbit and the clonality is Polyclonal, with no fluorophore or enzyme reporter conjugated, so users can pair it freely with their preferred secondary antibody or label it themselves. Purity is ensured by affinity purification using the IL1RN immunogen, and the preparation is formulated in a phosphate buffer at pH 7.4 containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol to preserve activity during routine handling. For best stability the vial should be stored according to the manufacturer's instructions (typically short-term at 4 °C, with longer-term aliquots kept at −20 °C to avoid repeated freeze/thaw cycles). The product is classified as a primary antibody and is labelled For Research Use Only — it is not intended for diagnostic or therapeutic applications. With a broad human–mouse–rat reactivity profile and a clean unconjugated format, this IL1RN polyclonal antibody is well suited to researchers investigating IL-1 pathway biology, cytokine regulation and inflammation-related targets.