Anti-IL1B Antibody

Manufactured by Antibodies.com, this affinity-purified reagent is a rabbit polyclonal antibody raised against recombinant human IL-1 beta (IL1B) protein and is supplied at a working concentration of 1.0 mg/mL in a 50 µl vial. The unconjugated antibody detects the endogenous total IL1B protein and is validated for Western blot (WB) and immunocytochemistry/immunofluorescence (ICC/IF) workflows, making it suitable for studies of cytokine signaling, inflammation, and innate immune response in cultured cells and tissue-derived samples. Cross-reactivity has been demonstrated against human, mouse, and rat samples, broadening its utility across comparative model systems. The host species is rabbit, the clonality is polyclonal, and the conjugate status is unconjugated, allowing end users to couple the reagent to their preferred reporter dye, biotin, or HRP secondary system as required by their assay. The formulation is provided in phosphate-buffered saline at pH 7.4 (without magnesium and calcium), containing 150 mM sodium chloride, 0.02% sodium azide as preservative, and 50% glycerol for cryoprotection; long-term storage should be at -20 °C, and repeated freeze/thaw cycles should be avoided to preserve binding activity. Also known by the synonyms Catabolin, IL1F2, and Interleukin-1 beta, this primary antibody is intended for research use only and is not approved for diagnostic or therapeutic applications.