Anti-IL17F Antibody

Raised in rabbits against the human cytokine IL17F, this unconjugated polyclonal reagent is supplied by Antibodies.com as a 100 µl aliquot for research use. IL17F (Interleukin-17F) is a pro-inflammatory cytokine expressed by activated Th17 cells and innate lymphoid cells, where it signals through the IL17 receptor complex to drive epithelial antimicrobial responses, neutrophil recruitment, and mucin production. The antibody is validated for Western blot and immunofluorescence workflows, making it a useful tool for mapping IL17F expression in tissue sections and confirming expression levels in cell lysates.

Because IL17F and IL17A share substantial sequence homology and can be co-expressed, antibody specificity matters when assigning inflammatory phenotypes to particular cell populations. The unconjugated format lets researchers pair it with HRP-, biotin-, or fluorophore-conjugated secondary antibodies of their own choice. For storage, keep the vial at -20 °C and divide into working aliquots to limit freeze-thaw cycles and preserve activity across studies of mucosal immunity, psoriasis models, and asthma or COPD research.