Anti-IL13 Antibody

Produced in rabbit as an unconjugated polyclonal IgG, this primary antibody from Antibodies.com binds human interleukin-13, a Th2-associated cytokine that drives IgE class switching, goblet cell hyperplasia, airway mucus hypersecretion, and subepithelial fibrosis in allergic airway disease. Supplied as 100 µl of antiserum in a single-use vial, the reagent is validated for Western blot, immunohistochemistry, and immunofluorescence on human samples and supports cytokine localization studies in research use only settings.

Researchers deploy the reagent to characterize IL13-producing Th2 lymphocytes, mast cells, eosinophils, and bronchial epithelial cells in asthmatic and atopic dermatitis biopsies, and to track cytokine expression in parasitic infection models and tumor microenvironments where IL13 contributes to immunosuppressive macrophage polarization. The polyclonal format provides multiple epitope coverage, useful when investigating IL13 splice variants or post-translationally modified cytokine forms.

For immunostaining, titrate on fixed human tissue; for immunofluorescence, pair with a fluorophore-conjugated anti-rabbit IgG secondary. Aliquot upon first thaw to limit freeze-thaw cycles and refrigerate for short-term use, or freeze in working aliquots for longer term stability.