Anti-IL1 beta Antibody [464]

This mouse monoclonal antibody, clone 464, specifically targets human Interleukin-1 beta (IL-1β), a potent pro-inflammatory cytokine produced by activated macrophages and monocytes. Generated in mouse hosts and of the IgM isotype, this unconjugated primary antibody from Antibodies.com is supplied as a 100 µg lyophilised preparation suited to ELISA workflows.

IL-1β plays a central role in innate immunity and orchestrates fever, leukocyte recruitment, and acute-phase responses following pathogen recognition. Scientists investigating inflammatory signalling cascades, cytokine release syndromes, or autoimmune disease pathogenesis rely on well-characterised IL-1β antibodies to quantify this cytokine in research samples and to probe inflammasome activity.

The lyophilised format simplifies storage and shipping, with the vial typically reconstituted in buffer before use. As an unconjugated reagent, the antibody offers flexibility for downstream labelling with reporter enzymes, fluorophores, or biotin, depending on the chosen assay design.