Anti-IL-9R Antibody

Probing the human Interleukin-9 Receptor (IL-9R) in cell lysates and immunoassays, this unconjugated rabbit polyclonal reagent from Antibodies.com is supplied as a 100 µL vial validated for Western blot and ELISA workflows. IL-9R is a type I cytokine receptor that pairs with the common gamma chain to transduce signals through JAK1, JAK3, and STAT proteins, shaping Th9 differentiation, mast cell activation, eosinophil responses, and B-cell class switching. The receptor is implicated in asthma pathology, atopic dermatitis, and certain Hodgkin lymphoma subtypes, where aberrant expression on Reed-Sternberg cells has been documented. This polyclonal format recognizes multiple epitopes across the extracellular and cytoplasmic regions of IL-9R, supporting detection of full-length receptor as well as putative truncated isoforms in human samples. Recommended for researchers investigating cytokine signaling, allergic inflammation, or hematologic malignancy models, the antibody is suited to membrane fraction preparations and total lysates from primary immune cells or established human cell lines. Refrigerated storage and limited freeze-thaw cycles preserve reagent activity for longitudinal studies.