Anti-IL-5Rα Antibody

A polyclonal reagent from Antibodies.com raised in rabbit is directed against the alpha subunit of the human interleukin-5 receptor, a type I cytokine receptor also known as CD125 that pairs with the common beta chain to drive eosinophil and basophil signaling. This unconjugated IgG preparation is supplied as 100 µl of liquid in a vial and is validated for Western blot and ELISA workflows against human samples. Researchers studying eosinophil activation, Th2-driven airway inflammation, allergic disease models, and downstream JAK2/STAT5 signaling pathways use this reagent to detect IL-5Rα expression in cell lysates and tissue-derived protein extracts. The polyclonal profile enables recognition of multiple epitopes across the extracellular domain, supporting reproducible detection in immunoblotting and plate-based immunoassays. Aliquoting upon receipt is recommended to limit repeated freeze-thaw cycles and preserve long-term reactivity. For research use only; not intended for diagnostic or therapeutic applications.