Anti-IL-22Rα2 Antibody

Primary antibodies targeting the IL-22 binding protein (IL-22Rα2, also known as IL-22BP) from Antibodies.com are useful for probing the natural antagonist that modulates IL-22 cytokine signaling at mucosal and epithelial surfaces. This rabbit polyclonal reagent is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial ready for western blot workflows. The antibody recognizes the human, mouse, and rat IL-22Rα2 target and is unconjugated, allowing flexible choice of secondary detection chemistry in downstream immunoblotting. Glycerol-containing aliquots should be stored at -20 °C in working volumes to limit freeze-thaw cycles, with brief handling on ice during western blot setup. Research applications include studies of epithelial barrier function, inflammatory skin disease models, intestinal mucosal immunity, and tissue-level regulation of Th17/Th22 cytokine responses.