Anti-IL-21 Antibody

Raised in rabbit and supplied as an unconjugated polyclonal reagent, this IL-21 antibody from Antibodies.com recognizes human Interleukin-21, a type I cytokine secreted by activated CD4+ T cells and NKT cells that signals through the IL-21 receptor and the common gamma chain. Validated for Western blot and ELISA workflows, the antibody cross-reacts with mouse IL-21 and is well suited to studies of B cell differentiation, germinal center responses, Th17 polarization, and NK cell maturation. Each vial delivers 100 µl of affinity-purified antiserum, providing multiple aliquots for probing stimulated peripheral blood mononuclear cell lysates, blotting membrane strips, or pairing with a matched secondary on ELISA plates. The polyclonal format broadens epitope coverage, helping researchers capture native IL-21 from transfected cell lines, primary lymphocyte cultures, and recombinant cytokine standards. Storage at -20°C in working aliquots preserves activity across repeated freeze-thaw cycles for ongoing bench use.