Anti-IL-18R Antibody

Rabbit polyclonal antibodies targeting the interleukin-18 receptor provide a useful reagent for investigating cytokine-driven inflammation and innate immune signaling. This unconjugated reagent from Antibodies.com is supplied at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, packaged as a 100 µl aliquot that supports multiple immunoblot and staining experiments.

The antibody recognizes IL-18R in human, mouse, and rat samples, enabling cross-species studies in models of inflammatory disease, autoimmune research, and Th1/NK-cell biology. Validated applications include Western blot (WB) for protein-level detection in cell lysates and tissue homogenates, and immunohistochemistry (IHC) for localization studies in fixed tissue sections. The polyclonal format increases the likelihood of detecting IL-18R even when expression is low or when the target undergoes partial degradation during sample preparation.

Storage and handling recommendations: aliquot upon receipt to minimize freeze-thaw cycles and store short term at 4 °C; for longer-term storage, keep frozen at -20 °C. Protect from light. The included 50% glycerol acts as a cryoprotectant to preserve antibody activity during routine freezer storage.