Anti-IL-13Rα1 Antibody

This rabbit polyclonal reagent from Antibodies.com targets Interleukin-13 receptor subunit alpha-1 (IL-13Rα1), a transmembrane protein that mediates JAK/STAT6 signaling downstream of IL-13 and IL-4 binding. Raised in rabbit and supplied as an unconjugated primary antibody in a 100 µl volume, it is validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows across human, mouse, and rat samples.

IL-13Rα1 partners with IL-4Rα to form the type II IL-4 receptor complex, making this reagent useful for studies of Th2-driven inflammation, allergic airway disease, asthma models, parasite immunity, and fibrotic tissue remodeling. Researchers commonly apply it to paraffin-embedded or frozen tissue sections, cultured cell lines, and primary cell lysates to map receptor distribution and pathway activation.

The polyclonal format allows recognition of multiple epitopes on the target, and aliquoting on receipt helps limit freeze-thaw cycles during long-term storage. Each vial is affinity-purified and validated for the listed applications, with sufficient material for multiple blotting and staining runs depending on dilution. Working concentration should be optimized empirically for each detection system and sample type.