Anti-IL-1β Antibody

Interleukin-1 beta (IL-1β) is a pro-inflammatory cytokine central to innate immune signaling, inflammasome activation, and the acute phase response. This polyclonal reagent from Antibodies.com is raised in rabbit, supplied as 100 µl of unconjugated liquid, and validated for western blot and ELISA across human, mouse, and rat samples, making it a practical tool for inflammation research, cytokine profiling, and studies of caspase-1-mediated cytokine processing.

The antibody detects both the 31 kDa pro-form and the 17 kDa mature form of IL-1β in cell lysates and tissue homogenates, supporting applications such as western blot analysis of macrophage or monocyte activation models and ELISA-based quantification of secreted cytokine in cell culture supernatants. Researchers commonly use it to investigate NLRP3 inflammasome activity, sterile inflammation, and disease models involving rheumatoid arthritis, sepsis, or neuroinflammation.

Provided by Antibodies.com as a primary antibody for research use only, the reagent is aliquoted on receipt for routine laboratory handling. Refrigerate on arrival for short-term use and freeze aliquots at -20 °C to preserve activity across multiple freeze-thaw cycles.