Anti-IL-1β Antibody

Raised in rabbit against human IL-1β (Interleukin-1 beta), this polyclonal antibody from Antibodies.com is supplied as an unconjugated IgG preparation at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol cryoprotectant. The reagent is validated for Western blot (WB) and immunohistochemistry (IHC) workflows and cross-reacts with mouse IL-1β in addition to the human target, making it useful across species-comparative inflammation studies. Each vial contains 100 µl of antibody, enough for multiple immunoblots or a panel of formalin-fixed tissue sections. IL-1β is a 17 kDa pro-inflammatory cytokine cleaved from its 31 kDa pro-form by caspase-1 following inflammasome assembly, and detecting the mature cleaved species is a common read-out in pyroptosis, autoinflammatory disease, and cytokine storm research. The polyclonal format recognises multiple epitopes on the target, supporting reliable signal in both denaturing SDS-PAGE separations and aldehyde-fixed tissue preparations. For best stability, the antibody should be stored at -20°C and aliquoted on first use to limit freeze-thaw cycles; the included sodium azide allows short-term bench handling without microbial contamination. Suitable for research use only in academic and translational laboratory settings.